Crowdcube, the private market investment platform, has launched its first transaction as part of its private securities market partnership with London Stock Exchange Group, using a TPEIC structure developed by TPE.
Through this structure, eligible investors can access economic exposure to Oxford Science Enterprises, the investment firm and venture builder operating in partnership with Oxford University. OSE’s portfolio spans AI, life sciences and deep technology emerging from Oxford’s research ecosystem.
TPEICs are designed to operate alongside established market infrastructure, enabling private-company exposures to be traded through permissioned auctions using exchange-connected systems, while the underlying companies remain private.
The use of PISCES and the LSE’s Private Securities Market enables intermittent trading, electronic settlement and standardised governance and disclosure processes.
At a time when companies are staying private for longer, access to structured liquidity solutions is becoming increasingly important for both shareholders and investors. This transaction demonstrates how private-market innovation, regulatory frameworks and public-market infrastructure can combine to create new pathways for accessing the UK’s most productive private assets.
The opportunity provides investors with diversified exposure to the commercial output of Oxford’s research in AI, machine learning, life sciences, health tech and deep tech, sectors driving global societal and economic transformation.
Matt Cooper, co-CEO of Crowdcube, said: “This offer provides Crowdcube investors with exclusive access via a newly approved structure, the TPEIC, to world-class deep-tech and life sciences companies founded on peer-reviewed scientific breakthroughs from the University of Oxford, the world’s top-ranked research institution.
“With more than £850 million raised and £1.8 billion in co-investment from global institutions, OSE is regarded as one of the world’s most advanced single-ecosystem venture builders in the world.
“We look forward to working closely with LSEG through 2026 to create more pathways for investors to buy shares in the most productive UK assets.”
Frederick Bouverat – founder and CEO of TPE, added: “We are proud to collaborate with Crowdcube on this inaugural TPEIC.
“Their platform has played a meaningful role in expanding participation in private markets, and their involvement strengthens the distribution framework supporting structured liquidity within LSEG’s PSM ecosystem.”


