Our aim at Neupulse is to improve the lives of people with Tourette Syndrome.

We have developed a non-invasive and drug free treatment that helps reduce tics and the urge to tic. This is achieved through gentle stimulation of the median nerve in the wrist.

The research

When we asked individuals with tic disorders and their families for their thoughts on our research priorities, we were frequently told that what was really needed was an effective drug free treatment for tic disorders that could be used outside of the clinic and gave individuals control over their tics. This led directly to us focusing on the use of peripheral nerve stimulation as a means of bringing about changes in the brain networks associated with the production of tics.

We demonstrated that delivering rhythmic patterns of mild electrical stimulation to the median nerve at the wrist could be used to increase the power and the synchronicity of the brain oscillations (rhythms) associated with the suppression of movements, and that this type of stimulation was sufficient to dramatically reduce the frequency of tics and remove the urge-to-tic in individuals with tic disorders.

Importantly, we also showed that this type of stimulation did not materially affect the execution of volitional (intentional) movements or impair cognitive functions such as attention.

Our solutions

At Neupulse, we are not just developing a medical device; we are pioneering a change in the Tourette syndrome therapeutic landscape. Our commercial strategy is focused on bringing this ground-breaking technology from the realm of clinical trials into the hands of those who need it most.

Neupulse-prototype

We are now dedicating our efforts to the development of a commercially available wearable wrist device that administers median nerve stimulation at the press of a button – with the aim of empowering individuals with Tourette Syndrome to manage their symptoms effectively and have control over their tics.

 We are also developing a phone app that will help individuals to manage their Neupulse device and the groundbreaking stimulation it provides.

• Control & adjust stimulation – Easily manage the device’s stimulation settings

• Personalised therapy – Customise intensity and duration to suit individual therapeutic needs

• Easy to use – The app has been designed with TS individuals and families in mind, allowing you to control multiple devices from the app using the simple and intuitive app interface

• Rigorously tested – Individuals with TS – young and old, along with families and healthcare professionals – have been involved throughout the development process

Neupulse